Science and Research
- Excess Weight & Obesity
- Insulin Resistance
- Ingredients
About Excess Weight and Obesity
About Cinnamon
- Cinnamon improves glucose and lipids of people with type 2 diabetes.
Obesity: Incidence 
- Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement.
- Avenell A, Broom J, Brown TJ, Poobalan A, Aucott L, Stearns SC, Smith WC, Jung RT, Campbell MK, Grant AM. Health Technol Assess. 2004 May;8(21):iii-iv, 1-182.
Obesity and Cardiovascular Disease
Obesity and Weight loss
Obesity and Nutrients/Diet
Obesity and Exercise 
Obesity and Support
Obesity and Mental Disorders
Obesity and Diabetes
Exercise and Cardiovascular disease
Obesity and Cancer 
- Diet,
body size, physical activity, and the risk of endometrial cancer.
- Goodman MT, Hankin JH, Wilkens LR, Lyu LC, McDuffie K, Liu LQ, Kolonel
LN.,Cancer Res. 1997 Nov 15;57(22):5077-85. PMID: 9371506
- Obesity,
weight gain and risk of colon adenomas in Japanese men.
- Kono S, Handa K, Hayabuchi H, Kiyohara C, Inoue H, Marugame T, Shinomiya
S, Hamada H, Onuma K, Koga H., Jpn J Cancer Res. 1999 Aug;90(8):805-11.
PMID: 10543250
- Risks
and benefits of estrogen plus progestin in healthy postmenopausal women:
principal results from the Women's Health Initiative randomized controlled
trial.
- Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick
ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene
J; Writing Group for the Women's Health Initiative Investigators., JAMA.
2002 Jul 17;288(3):321-33. PMID: 12117397
- International
renal-cell cancer study. III. Role of weight, height, physical activity,
and use of amphetamines.
- Mellemgaard A, Lindblad P, Schlehofer B, Bergstrom R, Mandel JS, McCredie
M, McLaughlin JK, Niwa S, Odaka N, Pommer W, et al., Int J Cancer. 1995
Jan 27;60(3):350-4. PMID: 7829243
- Adenocarcinoma
of the esophagus: role of obesity and diet.
- Brown LM, Swanson CA, Gridley G, Swanson GM, Schoenberg JB, Greenberg
RS, Silverman DT, Pottern LM, Hayes RB, Schwartz AG, et al., J Natl Cancer
Inst. 1995 Jan 18;87 (2):104-9. PMID: 7707381
- Body
mass index and risk of adenocarcinomas of the esophagus and gastric cardia.
- Chow WH, Blot WJ, Vaughan TL, Risch HA, Gammon MD, Stanford JL, Dubrow
R, Schoenberg JB, Mayne ST, Farrow DC, Ahsan H, West AB, Rotterdam H,
Niwa S, Fraumeni JF Jr., J Natl Cancer Inst. 1998 Jan 21;90(2):150-5.
PMID: 9450576
- Body
mass index and the risk of cancers of the gastric cardia and distal stomach
in Shanghai, China.
- Ji BT, Chow WH, Yang G, McLaughlin JK, Gao RN, Zheng W, Shu XO, Jin
F, Fraumeni JF Jr, Gao YT., Cancer Epidemiol Biomarkers Prev. 1997 Jul;6(7):481-5.
PMID: 9232333
- Association
of smoking, body mass, and physical activity with risk of prostate cancer
in the Iowa 65+ Rural Health Study (United States).
- Cerhan JR, Torner JC, Lynch CF, Rubenstein LM, Lemke JH, Cohen MB,
Lubaroff DM, Wallace RB., Breast Cancer Res. 2005;7(5):R833-43. Epub
2005 Aug 19. PMID: 16168130
- Dietary
and nutritional factors and pancreatic cancer: a case- control study based
on direct interviews.
- Silverman DT, Swanson CA, Gridley G, Wacholder S, Greenberg RS, Brown
LM, Hayes RB, Swanson GM, Schoenberg JB, Pottern LM, Schwartz AG, Fraumeni
JF Jr, Hoover RN., J Natl Cancer Inst. 1998 Nov 18;90 (22):1710-9. PMID:
9827525
- Changes
in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation
carriers.
- Kotsopoulos J, Olopado OI, Ghadirian P, Lubinski J, Lynch HT, Isaacs
C, Weber B, Kim-Sing C, Ainsworth P, Foulkes WD, Eisen A, Sun P, Narod
SA., Breast Cancer Res. 2005;7(5):R833-43. Epub 2005 Aug 19. PMID: 16168130
| "I have been studying Insulin
Resistance and have been doing quite a bit of research on this
subject. I really am impressed by your site as well as the sound
of your products to treat this syndrome."
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Carrie Power, APN |
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Elko, NV |
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About Insulin Resistance
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Insulin Resistance – Risk of Early Heart Disease
– Reuters
Aug 9, 2001 |
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Alternative Therapies for Type 2 Diabetes
– Lucy Dey MD, Chun-Su Yuan MD PHD |
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The role of insulin, insulin growth factor, and insulin-degrading enzyme in brain aging and Alzheimer's disease.
-Messier C, Teutenberg K.School of Psychology, University of Ottawa, Neural Plast. 2005;12(4):311-28 |
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Risk Factors and Life Expectancy Project, University of Buffalo, results presented at the annual meeting of the Society for Epidemiological Research.
– Paolo Muti MD, Jain Liu, Maurizio Trevisan MD, Alessandro Menotti,
University of Buffalo |
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The Ins and Outs of Insulin Resistance
– International Food Information Council. May/June 2000. |
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Insulin Resistance Syndrome
– Goutham Roa, M.D, Am Fam Physician 2001;63:1159-63,1165-6. |
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Relationship between Insulin Resistance, weight loss and coronary heart disease risk in healthy, obese women
– McLaughlin T, Abbasi F, Kim HS, Lamendola C, Schaaf P, Reaven G.
Department of Medicine, Stanford University School of Medicine Stanford, CA, USA
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F as in Fat: How Obesity Policies are Failing in America
– Trust for America's Health, 2005. |
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Ingredients
Other nutrients that heal Insulin Resistance
About Cinnamon
- Cinnamon improves glucose and lipids of people
with type 2 diabetes.
About Vanadium
- Effect of vanadium on insulin sensitivity and appetite.
- Effect of vanadium(IV) compounds in the treatment of diabetes: in vivo
and in vitro studies with vanadyl sulfate and bis(maltolato)oxovandium(IV).
- Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type
2 diabetes.
- Effect of long-term treatment with vanadate in drinking water on KK mice
with genetic non-insulin-dependent diabetes mellitus.
- Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent
diabetes mellitus: in vivo and in vitro studies.
- Vanadium and diabetes.
About Chromium
- Overproduction of insulin in the chromium-deficient rat.
- Chromium in the prevention and control of diabetes.
- Chromium as an essential nutrient for humans.
About Magnesium
- Magnesium in diabetes mellitus.
- Low dietary magnesium is associated with Insulin Resistance in a sample
of young, nondiabetic Black Americans.
- Effects of insulin on plasma magnesium in noninsulin-dependent diabetes
mellitus: evidence for Insulin Resistance.
About Alpha Lipoic Acid
- Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic
rats.
- Engagement of the insulin-sensitive pathway in the stimulation of glucose
transport by alpha-lipoic acid in 3T3-L1 adipocytes.
- Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany:
current evidence from clinical trials.
- Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy
metabolism in experimental diabetic neuropathy.
- Alpha-lipoic acid: a multifunctional antioxidant that improves insulin
sensitivity in patients with type 2 diabetes.
Omega-3 and Insulin Resistance
- N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent
insulin resistance associated to type 2 diabetes and obesity?
- Skeletal muscle membrane lipids and insulin resistance.
- Fatty acids, triglycerides and syndromes of insulin resistance.
- Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic
acids in gestational diabetes.
- Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing
cellularity of adipose tissue.
- In the 19th century, women attacking medicine
- N-3 long-chain polyunsaturated fatty acids in type 2 diabetes: a review.
- Influence of co-administration of oral insulin and docosahexaenoic acid
in mice.
- N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent
insulin resistance associated to type 2 diabetes and obesity?
- Assessment of the influence of fatty acids on indices of insulin sensitivity
and myocellular lipid content by use of magnetic resonance spectroscopy in
cats.
Omega-3 and Lipid Profiles
- Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential
associations with lipid responses.
- Docosahexaenoic and eicosapentaenoic acids in plasma phospholipids are
divergently associated with high density lipoprotein in humans.
- Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans
have similar triacylglycerol-lowering effects but divergent effects on serum
fatty acids.
- Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic
effect of fish oil in humans.
- Long-term effects of fish oil on insulin resistance and plasma lipoproteins
in NIDDM patients with hypertriglyceridemia.
- Increased n-6 polyunsaturated fatty acids do not attenuate the effects
of long-chain n-3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol
reduction in Indian Asians.
Omega-3 and Cardiovascular Disease (CVD)
- The effect of omega-3 fatty acids on risk factors for cardiovascular diseases.
- Fish-oil concentrate: effects on variables related to cardiovascular disease.
- Farmed and wild fish in the prevention of cardiovascular diseases: assessing
possible differences in lipid nutritional values.
- The Omega-3 Index: a new risk factor for death from coronary heart disease?
- Dietary fat quality: a nutritional epidemiologist's view.
- Docosahexaenoic acid affects insulin deficiency- and insulin resistance-induced
alterations in cardiac mitochondria.
- Fatty acids, triglycerides and syndromes of insulin resistance.
- Fish oil capsules lower in contaminants: study
Omega-3 and Hypertension
- Effect of docosahexaenoic acid on smooth muscle cell functions.
- Effect of docosahexaenoic acid on intracellular calcium dynamics in vascular
smooth muscle cells from normotensive and genetically hypertensive rats.
- Effects of docosahexaenoic acid on vascular pathology and reactivity in
hypertension.
- Vasorelaxant properties of n-3 polyunsaturated fatty acids in aortas from
spontaneously hypertensive and normotensive rats.
- Mechanisms of vasorelaxation induced by eicosapentaenoic acid (20:5n-3)
in WKY rat aorta.
- Docosahexaenoic acid--induced vasorelaxation in hypertensive rats: mechanisms
of action.
- Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation
in hypertensive rat aorta.
- Eicosapentaenoic acid inhibits Ca2+ mobilization and PKC activity in vascular
smooth muscle cells.
- Effects of eicosapentaenoic acid on cardiac SR Ca(2+)-release and ryanodine
receptor function.
- Long-chain polyunsaturated fatty acids, endothelial lipase and atherosclerosis.
Omega-3 and the Reduction in Inflammatory Markers
Associated with CVD 
- C-reactive protein is independently associated with fasting insulin in
nondiabetic women.
- Insulin resistance, inflammation, and serum fatty acid composition.
- Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory
markers among US men and women.
- Major dietary patterns are related to plasma concentrations of markers
of inflammation and endothelial dysfunction.
- Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation
and endothelial activation in women.
- Background diet influences the anti-inflammatory effect of alpha-linolenic
acid in dyslipidaemic subjects.
- Diet composition and insulin action in animal models.
- Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular
risk factors in hypercholesterolemic men and women.
- Dietary fatty acids affect plasma markers of inflammation in healthy men
fed controlled diets: a randomized crossover study.
Neurological Impact of Omega-3's 
- Omega-3 fatty acids in the treatment of psychiatric disorders.
- Essential fatty acids, DHA and human brain.
- Health benefits of docosahexaenoic acid (DHA).
- Brain development and assessing the supply of polyunsaturated fatty acid.
- Roles of unsaturated fatty acids (especially omega-3 fatty acids) in the
brain at various ages and during ageing.
- Essential fatty acids and the brain.
- Lipids, depression and suicide
- Omega-3 fatty acids and neuropsychiatric disorders.
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