Insulin Resistance creates increased levels of insulin and
glucose in the blood stream, which is a major underlying cause of excess
weight and obesity and their links to several other major disorders.
Combating these conditions is crucial for heart disease
prevention because Insulin Resistance, excess weight and obesity may increase the
risk of developing Metabolic Syndrome (Syndrome X). This latter
ailment can damage the cardiovascular system, specifically the lining of the
arteries, as well as creating a greater risk of blood clot formation. The
kidneys' ability to remove salt is also affected. All of these factors raise the
likelihood of developing Cardiovascular Disease (CVD) leading to a heart
attack or stroke.
A study published in the Journal of the American Medical
Association in December 2002 found that men with Metabolic
Syndrome were associated with a 2.6 - 3.0 times higher CVD
mortality rate and a 1.9 - 2.1 higher all-cause mortality rate
(1).
This breakthrough in understanding the body's biochemistry
remains relatively unknown, even though Insulin Resistance has reached epidemic
proportions. Your doctor may not have explained the crucial link between
Insulin Resistance, excess weight, obesity and Metabolic Syndrome. You
need to understand this link in order to help reverse the symptoms of
your condition.
The Insulite System for Excess Weight and Obesity is the first scientifically-designed program that restores your body's
ability to overcome Metabolic Syndrome by reversing Insulin Resistance.
Pre-Diabetes, Insulin Resistance, Excess Weight and Obesity
As an underlying cause of Pre-Diabetes, Insulin
Resistance-linked excess weight and obesity has many factors that contribute to its
presence in the body. In essence, our environment and lifestyles have evolved
too rapidly for our bodies to keep pace. We are still genetically "wired" to
thrive on the entrenched habits of our ancestors, who consumed different,
nutrient-rich foods, a diet low in carbohydrates and sustained greater
levels of movement and exercise. Some people may also have a genetic
predisposition to Insulin Resistance, while others develop the condition through high
stress and unhealthy lifestyles.
Over time, the above factors have damaged the complex ability
of the body's cells to properly utilize insulin to convert glucose to
energy. This process creates Insulin Resistance, which can lead to Pre-Diabetes in
two distinct ways.
First, Insulin Resistance vastly reduces the number of insulin
receptor sites, or doorways, on the walls of your cells. The
average healthy person has some 20,000 receptor sites per cell,
while the average overweight individual with Pre-Diabetes can
have as few as 5,000.
If you have too few receptor sites, glucose bounces off the
cell wall, instead of passing through the insulin door to be burned as
energy. With the cell door almost closed to it, glucose remains in the blood
stream, causing elevated levels of blood sugar, which are sent to the liver.
Once there, the sugar is converted into fat and carried via the blood stream
throughout the body. This process can lead to weight gain and obesity.
Insulin Resistance-linked excess weight and obesity underlie
Pre-Diabetes by raising insulin levels in the blood stream. Unhealthy
lifestyles and genetic conditions cause the pancreas to overproduce insulin. The
cell, in turn, is overwhelmed by this surplus insulin and protects itself by
reducing the number of its insulin receptor sites.
This process leaves too few sites for insulin to carry out its
normal function, which is to attach itself to the cell wall and act
as a "key in a lock" to allow glucose to pass through the cell wall and be
converted into energy. The vastly reduced number of receptor sites in Insulin
Resistant people causes an excess of insulin "rejected" by the cell to
float freely in the blood stream, which can damage the cardiovascular system.
Pre-Diabetes can be reversed. But if neglected, it can lead to
the onset of irreversible Type 2 Diabetes, which may require daily insulin
injections for the remainder of your life. Type 2 Diabetes significantly
increases one's risk for blindness, amputation and
life-threatening kidney disease, as well as a heart attack and stroke.
Insulin Resistance, Excess Weight, Obesity and PCOS
(Polycystic Ovarian Syndrome)
 PCOS is a major cause of infertility in women and is closely
linked to Insulin Resistance-related excess weight and obesity. This
condition is also known as polycystic ovaries, Sclerocystic Ovarian Disease,
Stein-Leventhal Syndrome, Chronic Anovulatory Syndrome and Polycystic Ovarian
Disease (PCOD).
It is the most common female endocrine (hormonal) disorder and
is characterized, in some cases, by multiple abnormal ovarian
cysts. Most ovarian cysts are harmless, fluid-filled sacs
containing immature eggs that attach to the ovaries. But
multiple cysts, with a typical appearance of a "string of
pearls" or "pearl necklace," are a hallmark of PCOS. An
estimated 5-10% of women of childbearing age are affected by
PCOS, which can prevent ovulation, making pregnancy impossible.
Post-menopausal women can also suffer from PCOS.
This reversible condition can be a silent killer. Since the
symptoms of PCOS often vary so widely from woman to woman, doctors sometimes
misdiagnose the condition. This oversight became a matter of critical concern
after a study conducted in 2000 found that women suffering from PCOS have a
higher risk of coronary heart disease (2).
Symptoms of PCOS can include excessive weight gain and obesity,
irregular, heavy or completely absent periods, ovarian cysts, an
overabundance of facial or body hair, Alopecia (male pattern
hair loss), acne, skin tags (growths from the skin), Acanthosis
Nigricans (brown skin patches) high cholesterol levels,
exhaustion or lack of mental alertness, depression, decreased
sex drive and excess male hormones.
There is no single pill that reverses Insulin Resistance, which
clearly needs to be controlled and reduced in the case of many
people suffering attendant disorders like excess weight gain and
obesity, Metabolic Syndrome, Pre-Diabetes and PCOS.
What is required is a complete system, including
nutraceuticals (vitamins, herbs and minerals that are disease-specific), a realistic
exercise program, nutritional guidance and a support network that will help you
change unhealthy lifestyle choices.
The Insulite System for Excess Weight and Obesity is
scientifically-designed to reverse Insulin Resistance by restoring the balance of
circulating blood sugar and insulin levels - crucial factors in first
stabilizing weight and then reducing it to a healthy level. Key components of the
Insulite System include advice on a balanced, nutritious diet and regular
exercise.
You may be interested in some Frequently Asked
Questions (FAQs) about the Insulite System for Weight
Gain and Obesity.
(1)
The metabolic syndrome and total and cardiovascular
disease mortality in middle-aged men.
- Lakka HM,
Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J,
Salonen JT., JAMA. 2002 Dec 4;288(21):2709-16.
PMID: 12460094
(2)
Evidence for Association Between Polycystic Ovary
Syndrome and Premature Carotid Atherosclerosis in Middle-Aged
Women
- Evelyn O. Talbott; David S. Guzick; Kim
Sutton-Tyrrell; Kathleen P. McHugh-Pemu; Jeanne V. Zborowski;
Karen E. Remsberg; Lewis H. Kuller, Arteriosclerosis,
Thrombosis, and Vascular Biology. 2000;20:2414.
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